Teriflunomide
CAS No.
163451-81-8
Molecular Weight
270.211 g·mol−1
Molecular Formula
C12H9F3N2O2
Granule: Available
Ready to press þ
Ready to fill o
Mechanism Of Action:
It’s a selective and reversible inhibitor of dihydro-orotate dehydrogenase, which is a key mitochondrial enzyme in the de novo pyrimidine synthesis pathway, leading to a reduction in proliferation of activated B and T lymphocytes without causing cell death.
Indication:
Teriflunomide is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.